The Motion Modelling and Analysis Group (MMAG) is an academic research group based within the School of Biomedical Engineering and Imaging Sciences of King's College London. The group is based at St. Thomas' Hospital in central London.
The MMAG has worked extensively in the past on the imaging, modelling and estimation of repetitive motion. Organ motion due to respiration and the beating of the heart is approximately periodic, so measurements of this motion made from imaging data can be used to construct mathematical models of the periodic motion and its variability. Such models can be applied to update guidance information in image-guided interventions or to correct acquired imaging data for the corrupting effects of motion. The group has worked on applying such models in a range of applications, but predominantly in the context of image-guided cardiac interventions and PET-MR imaging.
Currently, the main research theme of the group is the analysis of motion with the aim of extracting clinically useful biomarkers. Here, work focuses on cardiac cycle motion, in which changes in heart function will manifest themselves as subtle changes in the observed motion of the heart as it beats. The group works on developing novel machine learning techniques to learn motion features that are useful for a range of clinical prediction tasks.
The group is also involved in developing machine learning solutions to other problems, such as radiotherapy and vocal tract imaging.
- 6 February 2020: New paper by Esther Puyol-Antón on Deep learning based analysis of ShMOLLI T1 mapping from the UK Biobank dataset - out now on Arxiv.
- 10 September 2019: Accepted MICCAI 2019 workshop papers now have preprints available online:
- Esther Puyol-Antón et al (STACOM), Assessing the Impact of Blood Pressure on Cardiac Function Using Interpretable Biomarkers and Variational Autoencoders - see project summary.
- Nick Byrne et al (PIPPI), Topology-preserving Augmentation for CNN-based Segmentation of Congenital Heart Defects from 3D Paediatric CMR - see project summary.
- 18 July 2019: New paper by Esther Puyol-Antón and Bram Ruijsink on Fully Automated, Quality-Controlled Cardiac Analysis From CMR - see project summary.
- 11 July 2019: New textbook available - Statistics for Biomedical Engineers and Scientists:
- 18 June 2019: Accepted MICCAI 2019 papers now have preprints available online:
- 18 June 2019: Accepted MIDL 2019 papers available on OpenReview:
- 3 May 2019: New Medical Image Analysis paper by Ilkay Oksuz on Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning - see project summary.
- 6 Mar 2019: James Clough's work on incorporating topological knowledge into deep learning based image segmentation has been accepted for oral presentation at IPMI 2019. Preprint available here - see project summary.
- 22 Feb 2019: Data download now available for MRI images used in Clough et al, IEEE T-PAMI 2019.
- 17 Jan 2019: New IEEE-TPAMI paper by James Clough: "Weighted Manifold Alignment using Wave Kernel Signatures for Aligning Medical image Datasets" - see project summary.